| | U.S. Central | text only | |
| Sunday, September 20 |
| 12:00n |
31 |
Arizona Cardinals (10-6) |
at |
17 |
Jacksonville Jaguars (7-9) |
| 12:00n |
20 |
Carolina Panthers (8-8) |
at |
28 |
Atlanta Falcons (9-7) |
| 12:00n |
31 |
Cincinnati Bengals (10-6) |
at |
24 |
Green Bay Packers (11-5) |
| 12:00n |
34 |
Houston Texans (9-7) |
at |
31 |
Tennessee Titans (8-8) |
| 12:00n |
27 |
Minnesota Vikings (12-4) |
at |
13 |
Detroit Lions (2-14) |
| 12:00n |
9 |
New England Patriots (10-6) |
at |
16 |
New York Jets (9-7) |
| 12:00n |
48 |
New Orleans Saints (13-3) |
at |
22 |
Philadelphia Eagles (11-5) |
| 12:00n |
13 |
Oakland Raiders (5-11) |
at |
10 |
Kansas City Chiefs (4-12) |
| 12:00n |
7 |
St. Louis Rams (1-15) |
at |
9 |
Washington Redskins (4-12) |
| 3:05p |
10 |
Seattle Seahawks (5-11) |
at |
23 |
San Francisco 49ers (8-8) |
| 3:05p |
20 |
Tampa Bay Buccaneers (3-13) |
at |
33 |
Buffalo Bills (6-10) |
| 3:15p |
31 |
Baltimore Ravens (9-7) |
at |
26 |
San Diego Chargers (13-3) |
| 3:15p |
6 |
Cleveland Browns (5-11) |
at |
27 |
Denver Broncos (8-8) |
| 3:15p |
15 |
Pittsburgh Steelers (9-7) |
at |
17 |
Chicago Bears (7-9) |
| 7:20p |
33 |
New York Giants (8-8) |
at |
31 |
Dallas Cowboys (11-5) |
| |
| Monday, September 21 |
| 7:30p |
27 |
Indianapolis Colts (14-2) |
at |
23 |
Miami Dolphins (7-9) |
| |
